{"id":2036,"date":"2018-03-14T19:21:26","date_gmt":"2018-03-14T19:21:26","guid":{"rendered":"https:\/\/news.medicalmarijuanainc.com\/?p=30880"},"modified":"2018-03-14T19:21:26","modified_gmt":"2018-03-14T19:21:26","slug":"cannabis-flavonoids-role-play-cannabis","status":"publish","type":"post","link":"https:\/\/medicalmarijuanainc.com\/2018\/03\/14\/cannabis-flavonoids-role-play-cannabis\/","title":{"rendered":"What are Cannabis Flavonoids and What Role Do They Play in Cannabis?"},"content":{"rendered":"<p><i><span style=\"font-weight: 400;\">Cannabis flavonoids play an important role in the odor and flavor differences between marijuana strain varieties.<\/span><\/i><\/p>\n<p><span style=\"font-weight: 400;\">Of the more than 200-plus active compounds in cannabis, often times the not-as-well-understood flavonoids get overlooked.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">While they only make up around 10 percent of all the compounds in cannabis, flavonoids play an important role in the smell, taste, color, and effects of<\/span> <a href=\"https:\/\/medicalmarijuanainc.com\/\"><span style=\"font-weight: 400;\">medical marijuana<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Researchers have yet to come close to fully understanding the potential of cannabis flavonoids and more studies are desperately needed. Still, several appear to have some health benefits, including antioxidant and anti-inflammatory properties. Additionally, some researchers believe that cannabis flavonoids work in conjunction with cannabinoids and terpenes to promote wellness.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Here we discuss cannabis flavonoids, including what they are, the role they play in the appearance and flavor of your favorite strains, and what studies have so far found about their benefits.<\/span><\/p>\n<h2><b>What are Cannabis Flavonoids?<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Cannabis flavonoids are a naturally occurring group of phytonutrients that are responsible for the vivid non-green color pigments in marijuana and <\/span><a href=\"https:\/\/medicalmarijuanainc.com\/the-basics-of-hemp\/\"><span style=\"font-weight: 400;\">hemp plants<\/span><\/a><span style=\"font-weight: 400;\">. Flavonoids are also responsible for helping protect the health of cannabis plants by filtering out UV rays and preventing diseases, pests, and fungi.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Flavonoids are not unique to cannabis. In fact, over 6,000 individual flavonoids have been identified and many are found in the fruits, vegetables, and herbs that we routinely consume. Scientists have found that they play an important role in the smell, taste, and non-green colors of plants throughout nature.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The word flavonoid comes from the Latin term \u201cflavus,\u201d meaning yellow and referencing the compound\u2019s role in providing plants with their respective color pigmentation. The bright blue color in blueberries and vivid red color in red roses, for example, are due to flavonoids.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">There are some flavonoids that are exclusive to cannabis plants like marijuana and hemp. These cannabis-exclusive flavonoids are known as cannaflavins. The compounds are found readily in<\/span> <a href=\"https:\/\/medicalmarijuanainc.com\/beginners-guide-curing-cannabis\/\"><span style=\"font-weight: 400;\">cured marijuana flower<\/span><\/a><span style=\"font-weight: 400;\"> and leaves. Commonly grouped together, cannabis flavonoids are thought to supplement the other cannabis phytonutrients to play a highly bioactive role in the plant\u2019s consumption and cultivation.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">There are thought to be some 20 flavonoids thought to be in cannabis, some of which include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Cannaflavin-A (cannaflavin)<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Cannaflavin-B (cannaflavin)<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Cannaflavin-C (cannaflavin)<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Quercetin<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Isovitexin<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Apigenin<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Beta-Sitosterol<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Luteolin<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Orientin<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Kaempferol<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Catechins<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Vitexin<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">The distribution of cannaflavins varies depending on the strain of cannabis and growing conditions. They play an important role in providing the odor and flavor differences between<\/span> <a href=\"https:\/\/medicalmarijuanainc.com\/7-popular-cannabis-strains-dispensaries\/\"><span style=\"font-weight: 400;\">marijuana strain varieties<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h2><b><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-full wp-image-31150\" src=\"https:\/\/www.medicalmarijuanainc.com\/wp-content\/uploads\/2018\/03\/mjna-blog-images-marijuana-grow-tent-10-19-16-ver1-1.png\" alt=\"\" width=\"1200\" height=\"500\" \/><\/b><\/h2>\n<h2><\/h2>\n<h2><b>What Do Cannabis Flavonoids Do?<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Besides contributing to the color, taste, smell, and overall sensory experience of cannabis, flavonoids are also pharmacologically active compounds that may have medicinal benefits.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Evidence suggests that flavonoids work synergistically with cannabinoids like cannabidiol (<\/span><a href=\"https:\/\/medicalmarijuanainc.com\/what-is-cbd-hemp-oil\/\"><span style=\"font-weight: 400;\">CBD<\/span><\/a><span style=\"font-weight: 400;\">) and tetrahydrocannabinol (THC), and<\/span> <a href=\"https:\/\/medicalmarijuanainc.com\/terpenes-terpenoids-matter\/\"><span style=\"font-weight: 400;\">terpenes<\/span><\/a><span style=\"font-weight: 400;\"> like myrcene and limonene, to contribute to the range of <\/span><span style=\"font-weight: 400;\">effects<\/span><span style=\"font-weight: 400;\"> produced by cannabis. A theory called the \u201c<\/span><a href=\"https:\/\/medicalmarijuanainc.com\/can-hemp-oil-provide-entourage-effect\/\"><span style=\"font-weight: 400;\">entourage effect<\/span><\/a><span style=\"font-weight: 400;\">\u201d maintains that all the compounds in cannabis \u2013 such as flavonoids, cannabinoids, and terpenes \u2013 work together to influence the body\u2019s <\/span><a href=\"https:\/\/medicalmarijuanainc.com\/endocannabinoid-system\/\"><span style=\"font-weight: 400;\">endocannabinoid system<\/span><\/a><span style=\"font-weight: 400;\"> and magnify the natural beneficial effects of cannabis.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Cannabis flavonoids are non-psychoactive, which means they will not cause a euphoric high like the well-known cannabinoid THC. In fact, flavonoids are thought to subdue the psychoactive properties of THC.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Researchers have also <\/span><a href=\"https:\/\/medicalmarijuanainc.com\/dr-titus-insights-nsaids-flavonoids-autism\/\"><span style=\"font-weight: 400;\">started to investigate<\/span><\/a><span style=\"font-weight: 400;\"> the potential therapeutic properties of individual cannabis flavonoids. Cannabis flavonoids are vastly understudied, but so far, the findings suggest that cannabis flavonoids may possess<\/span> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28891090\"><span style=\"font-weight: 400;\">beneficial properties<\/span><\/a><span style=\"font-weight: 400;\"> related to their anti-oxidative, anti-inflammatory, and even anticarcinogenic effects that promote health.<\/span><\/p>\n<p><strong>Cannaflavin-A and Cannaflavin-B<\/strong><\/p>\n<p><span style=\"font-weight: 400;\">Recently, Cannaflavin-A and Cannaflavin-B were found to have powerful anti-inflammatory properties. In one<\/span> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/3754224\"><span style=\"font-weight: 400;\">study<\/span><\/a><span style=\"font-weight: 400;\">, Cannaflavin-A and Cannaflavin-B effectively inhibited PGE-2, a prostaglandin responsible for inflammation, in a similar manner as aspirin but exponentially more powerful than the common, over-the-counter medicine.<\/span><\/p>\n<p><strong>Catechins<\/strong><\/p>\n<p><span style=\"font-weight: 400;\">Researchers have found that Catechins, which is also found in cocoa, teas, and other pome fruits,<\/span> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2748751\/\"><span style=\"font-weight: 400;\">promotes cardiovascular health<\/span><\/a><span style=\"font-weight: 400;\"> because of its antioxidative, anti-hypertensive, anti-inflammatory, and anti-proliferative effects, as well as helping to<\/span> <a href=\"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002-8223(11)01379-4\"><span style=\"font-weight: 400;\">maintain healthy cholesterol levels<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><strong>Quercetin<\/strong><\/p>\n<p><span style=\"font-weight: 400;\">Quercetin, also found in many fruits and vegetables, is known for being an<\/span> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21445799\"><span style=\"font-weight: 400;\">antioxidant<\/span><\/a><span style=\"font-weight: 400;\"> and for having anti-viral properties that effectively<\/span> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4728566\/\"><span style=\"font-weight: 400;\">inhibit the Influenza A virus<\/span><\/a><span style=\"font-weight: 400;\">. <\/span><\/p>\n<p><strong>Beta-Sitosterol<\/strong><\/p>\n<p><span style=\"font-weight: 400;\">Beta-sitosterol, a cannabis flavonoid also found in nuts and avocados, has demonstrated<\/span> <a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mnfr.200900012\/abstract\"><span style=\"font-weight: 400;\">anti-inflammatory properties<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><strong>Vitexin and Isovitexin<\/strong><\/p>\n<p><span style=\"font-weight: 400;\">In both in vitro and in vivo studies, Vitexin and Isovitexin have shown to have anti-cancer effects. One<\/span> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28891090\"><span style=\"font-weight: 400;\">research review<\/span><\/a><span style=\"font-weight: 400;\"> found evidence that the two cannabis flavonoids are \u201cchemopreventive\u201d and act against cancer by encouraging the degradation or death of cancerous cells.<\/span><\/p>\n<p><strong>Orientin<\/strong><\/p>\n<p><span style=\"font-weight: 400;\">One of the most commonly extracted flavonoids from plants, Orientin has shown to have a wide array of beneficial properties. A<\/span> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4889806\/\"><span style=\"font-weight: 400;\">comprehensive review<\/span><\/a><span style=\"font-weight: 400;\"> investigating the medicinal properties of Orientin concluded that the flavonoid has antioxidant, anti-aging, anti-viral, anti-bacterial, anti-inflammatory, vasodilation and cardioprotective, radiation protective, neuroprotective, anti-depressant, anti-adipogenesis, and pain-relieving properties.<\/span><\/p>\n<p><strong>Apigenin<\/strong><\/p>\n<p><span style=\"font-weight: 400;\">Among the best studied of the flavonoids found in cannabis, Apigenin has demonstrated<\/span> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/7617761\"><span style=\"font-weight: 400;\">anti-anxiety<\/span><\/a><span style=\"font-weight: 400;\"> and<\/span> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18038911\"><span style=\"font-weight: 400;\">anti-inflammatory properties<\/span><\/a><span style=\"font-weight: 400;\">. The estrogenic properties of Apigenin have<\/span> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2559959\/\"><span style=\"font-weight: 400;\">shown<\/span><\/a><span style=\"font-weight: 400;\"> to<\/span> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4610175\/\"><span style=\"font-weight: 400;\">inhibit the growth of breast cancer cells<\/span><\/a><span style=\"font-weight: 400;\"> in several<\/span> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1716010\/\"><span style=\"font-weight: 400;\">studies<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-30882\" src=\"https:\/\/www.medicalmarijuanainc.com\/wp-content\/uploads\/2018\/03\/4-2-3.jpg\" alt=\"cannabis flavonoids definition\" width=\"1200\" height=\"500\" \/><\/p>\n<h2><b>Are Cannabis Flavonoids Legal?<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">While cannabis flavonoids aren\u2019t specifically listed as controlled substances under United States federal law,<\/span> <a href=\"https:\/\/news.medicalmarijuanainc.com\/the-road-to-prohibition-why-did-america-make-marijuana-illegal-in-the-first-place\/\"><span style=\"font-weight: 400;\">marijuana is<\/span><\/a><span style=\"font-weight: 400;\">. The 1970 Controlled Substances Act prohibits the use, possession, cultivation, and distribution of cannabis. This act makes cannaflavins, those flavonoids exclusively found in cannabis, illegal to obtain under federal law.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Despite cannabis being illegal under federal law, <\/span><a href=\"https:\/\/medicalmarijuanainc.com\/where-is-marijuana-legal\/\"><span style=\"font-weight: 400;\">more than 30 U.S. states and Washington D.C.<\/span><\/a><span style=\"font-weight: 400;\"> have legalized<\/span> <a href=\"https:\/\/medicalmarijuanainc.com\/\"><span style=\"font-weight: 400;\">medical marijuana<\/span><\/a><span style=\"font-weight: 400;\">, and more than 10 of those states plus Washington D.C. have also legalized recreational marijuana.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Unfortunately, despite some states legalizing marijuana, federal prohibition has hindered the volume of research in regards to cannabis flavonoids. Researchers interested in investigating the therapeutic potential of cannaflavins face regulatory hurdles and additional costs that make conducting studies difficult. To more thoroughly understand the role that cannabis flavonoids can play in health, it is extremely important that federal restrictions on cannabis be lifted.<\/span><\/p>\n<h2><b>All You Need to Know About Marijuana<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">With medical marijuana becoming legal throughout the U.S., many are looking to discover more about its effects and how to legally obtain it. If you are interested in learning more about the basics of medical marijuana and its compounds, visit our<\/span> <a href=\"https:\/\/medicalmarijuanainc.com\/\"><span style=\"font-weight: 400;\">Cannabis 101 page<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cannabis flavonoids play an important role in the odor and flavor differences between marijuana strain varieties of the more than 200-plus active compounds in cannabis, often times the not-as-well-understood flavonoids get overlooked.<\/p>\n","protected":false},"author":1,"featured_media":2037,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[7,38],"tags":[],"class_list":["post-2036","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cannabis-101","category-the-plant"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>What are Cannabis Flavonoids and What Role Do They Play in Cannabis? - Medical Marijuana, Inc.<\/title>\n<meta name=\"description\" content=\"Cannabis flavonoids play an important role in the odor and flavor differences between marijuana strain varieties. 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